Academic Publications


Determination of subcellular compartment sizes for estimating dose variations in radiotherapy

Poole, C.M., Ahnesjo, A., Enger, S.A.

Radiation Protection Dosimetry

The aim of this study was to develop an algorithm to derive cell and cell nuclei size distributions from 2D histology samples, and build 3D cellular geometries to provide Monte Carlo (MC)-based dose calculation engines with a morphologically relevant input geometry.


A feasibility study for using ABS plastic and a low-cost 3D printer for patient-specific brachytherapy mould design

Harris, B.D., Nilsson S., Poole, C.M.

Australasian Physical & Engineering Sciences in Medicine

This feasibility study aims to determine if a low-cost 3D printer (BitsFromBytes 3D Touch) with ABS plastic can print custom mould structures and catheter channels defined in a brachytherapy treatment planning system (Nucletron Oncentra) for patient-specific treatment.


Towards online patient imaging during helical radiotherapy

Yu. L., Poole, C.M., Lancaster, C.M., Sylvander, S.R.

Australasian Physical & Engineering Sciences in Medicine

The exit-detector data from Tomotherapy treatment procedures contain valuable photon exit fluence maps which can be utilised for contour definition and verification of patient alignment without reconstruction.


Dual acquisition of 18F-FMISO and 18F-FDOPA

Bell, C., Rose, S., Puttick, S., Pagnozzi, A., Poole, C.M., Gal, Y., Thomas, P., Fay, M., Jeffree, R.L., Dowson, N.

Physics in Medicine and Biology

Performing multiple PET acquisitions is impractical in many clinical settings, but previous studies suggest multiplexed PET imaging could be viable. The contribution of this work is to propose a framework to explicitly trade-off signal fidelity with logistical constraints when designing the imaging protocol.


Recent advances in radiotherapy for thoracic tumours

Fay, M., Poole, C.M., Pratt, G.

Journal of Thoracic Disease

This review outlines some of the advances in technology and radiotherapy treatment of thoracic cancers including brachytherapy, stereotactic radiotherapy, tomotherapy and intensity modulated radiotherapy.


Radiotherapy Monte Carlo simulation using cloud computing technology

CM Poole, I Cornelius, JV Trapp and CM Langton

Australasian Physical and Engineering Sciences in Medicine

Here we describe a technique that allows for Monte Carlo radiotherapy dose calculations to be performed using GEANT4 and executed in the cloud.


Fast tessellated solid Navigation in GEANT4

CM Poole, I Cornelius, JV Trapp and CM Langton

IEEE Transations on Nuclear Science

Here within we describe a technique that allows for automatic tetrahedral meshing of tessellated solids in GEANT4 and the subsequent loading of these meshes as assembly volumes.


A CAD Interface for GEANT4

CM Poole, I Cornelius, JV Trapp and CM Langton

Australasian Physical and Engineering Sciences in Medicine

Here we describe a technique that allows for CAD models to be directly loaded as geometry without the need for commercial software and intermediate file format conversion.


A hybrid radiation detector for simultaneous spatial and temporal dosimetry

CM Poole, JV Trapp, J Kenny, T Kairn, K Williams, M Taylor, R Franich and CM Langton

Australasian Physical and Engineering Sciences in Medicine

In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D experimental measurement of a radiation field.


Rayleigh theory of ultrasound scattering applied to liquid-filled contrast nanoparticle

Flegg, M.B., Poole, C.M., Whittaker, A.K., Keen, I. and Langton, C.M.

Physics in Medicine and Biology

We present a novel modified theory based upon Rayleigh scattering of ultrasound from composite nanoparticles with a liquid core and solid shell.


Effects of collimator backscatter in an Elekta linac by Monte Carlo simulation

Kairn, T., Crowe, S.B., Poole, C.M., Fielding, A.L.

Australasian Physical & Engineering Sciences in Medicine

The effects of radiation backscattered from the secondary collimators into the monitor chamber in an Elekta linac (producing 6 and 10 MV photon beams) are investigated using BEAMnrc Monte Carlo simulations.


Copyright, Christopher Poole 2008-2016.